Below are the current limitations of OneDrive for Business as of April 1, 2016 that ITS is aware of:
Number of items that can be synced
- The limit to sync files is gone with the new client.
- You can sync up to 5,000 items in a SharePoint library. This includes folders and files. These are the libraries that you find on various SharePoint sites, such as team sites and community sites, libraries that other people created, or that you created from your Sites page. This also includes syncing other people's OneDrive personal sites that you may have access to. You can sync multiple SharePoint libraries.
Size limit for syncing files
In OneDrive for Business, you can sync a file up to 10 GB.
Character limit for files and folders
These limits apply to files and folders that you add to a synced library folder for uploading to SharePoint.
- File names can have up to 128 characters.
- Folder names can have up to 250 characters.
- Folder name and file name combinations can have up to 250 characters.
The following characters in file names aren't supported when you sync OneDrive for Business with SharePoint Online:
Additionally, a file name that begins with a period (.) or a tilde (~) isn't supported.
SharePoint Server 2013
The following characters in file name aren't supported when you sync OneDrive for Business with SharePoint Server 2013:
Here too, a file name that begins with a period (.) or a tilde (~) isn't supported.
Unsupported folder name
When you sync OneDrive for Business with SharePoint Online or SharePoint 2013, a folder named "forms" isn't supported at the root level for a list or library. This occurs because "forms" is a hidden default folder that's used to store templates and forms for the library.
GUID strings as file names
The following GUID string structure isn't supported for file names in SharePoint 2013:
For example, a GUID that matches this structure resembles the following:
Note The GUID string structure is supported in SharePoint Online.
Invalid file types
You can't upload files that have a *.tmp or *.ds_store extension, and you can't upload desktop.ini, thumbs.db, or ehthumbs.db files.
Additionally, you can't upload files whose file types are blocked on the SharePoint site. If your organization is running SharePoint Server, the list of blocked files may vary, depending on what your administrator sets up. If your organization is running SharePoint Online, the default list of blocked files is fixed and can't be changed. To see a list of the default blocked files, go to the following Microsoft website:
Open files can't be synced
Any file that’s currently open by an application (for example, an Excel .xlsx file) can't be synced by OneDrive for Business.
To sync the file, close any application where the file is currently being used, and then sync the file.
The above information comes from: http://support.microsoft.com/kb/2933738